"Gene identified the prevents stem cells from turning Cancerous"
October 15, 2010 Article Source: Rockefeller University
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Summary: Research from Rockefeller University shows that having too many stem cells or cells that have lived too long increase your chance of cancer. Apparently a gene called Sept4 has a protein called ARTS and the lack of the protein can increase your cancer risk. To prove this, they bred some mice that lack the ARTS protein and in doing so, they had about twice as many hemotopoietic stem cells as the mice that had the ARTS protein. the ARTS deprived mice ended up getting spontaneous tumors at twice the rate as the regular mice. ARTS interferes with an inhibitor of apoptosis proteins that causes cells to not be able to kill themselves. Thus having a lot of the ARTS protein allows cells to die on schedule.
Significance: Knowing about the ARTS protein, maybe scientists can reproduce it and help prevent cancer.
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